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What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes? This project covers the mitigation of cardiovascular disease risk in patients with diabetes using optimal treatment regimens. Specifically, the proposed project is concerned with the stratification of cardiovascular disease risk in older adults with type 2 diabetes, using supervised machine learning methods based on electronic medical records databases, with the aim to tailor glucose lowering treatment regimens for high-risk patients that will

What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes? Previously, we observed that visit-to-visit variability in blood pressure was linked to heart failure, which is known to be 2.5 more likely in persons with type 2 diabetes (T2D). In this project, I will explore whether variability in blood pressure or variability in triglycerides exacerbates risk of heart failure in persons with T2D. This work will be conducted in T2D patients enrolled in both clinical trials and those recorded in a large

What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes? Obesity is a significant public health problem associated with an increased risk of developing type 2 diabetes (T2D). Over the past 20 years, the brain has been identified as a major contributor in the development to obesity/T2D. Our aim is to increase fundamental knowledge about the brain mechanisms involved in obesity/T2D. The findings from experiments described in the present proposal will impact the field of diabetes at the academic and pre