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What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes? This project primarily focuses on pre-type 1 diabetes, specifically the time period after autoimmunity has developed but before a person is clinically diagnosed with the disease. This is the time in disease progression that we seem to know the least about and is also the best time to intervene in disease progression to protect against further damage to the insulin-producing ?-cells in the islets of Langerhans. The goal of this study is to better