We are excited to highlight a select group of abstracts that have been chosen for recognition at the 84th Scientific Sessions in Orlando. You can find these abstracts in the Scientific Sessions Meeting App.
ADA Presidents’ Select Abstracts
The following abstracts were identified as noteworthy by the Scientific Sessions Meeting Planning Committee Chair and are being presented at the 84th Scientific Sessions as oral presentations:
9-OR: Targeting Inflammation with Salsalate in Type 1 Diabetes Neuropathy (TINSAL-T1DN Trial)
LYNN ANG, YIYUAN HUANG, CATHERINE MARTIN, KARA R. MIZOKAMI-STOUT, YU KUEI LIN, ALEXI VASBINDER, MOUSUMI BANERJEE, SALIM HAYEK, EVA L. FELDMAN, RODICA BUSUI, Ann Arbor, MI
17-OR: Oral Bisphenol A Administration Decreased Peripheral Insulin Sensitivity in Healthy Adults
ADAM SEAL, STEVEN K. MALIN, ANDREW SCHAFFNER, MICHAEL R. HUBBARD, SARAH K. KEADLE, HANNAH BRUNNER-GAYDOS, ALIA A. ORTIZ, JANE E. NAKAMURA, CLARA MCMAHON, RACHEL BARNETT, ANITA H. KELLEHER, KELLY A. BENNION, SUZANNE PHELAN, TODD HAGOBIAN, San Luis Obispo, CA, New Brunswick, NJ, Gilbert, AZ, San, CA, Seattle, WA, San Francisco, CA
74-OR: CGM Metrics from Five Studies Identify Participants at High Risk of Imminent Type 1 Diabetes (T1D) Development
PETER CALHOUN, CHARLEY SPANBAUER, ANDREA STECK, BRIGITTE I. FROHNERT, MARK A. HERMAN, BART KEYMEULEN, SR., RIITTA VEIJOLA, JORMA TOPPARI, ASTER DESOUTER, FRANS K. GORUS, MARK A. ATKINSON, DARRELL M. WILSON, SUSAN PIETROPAOLO, ROY BECK, Tampa, FL, Aurora, CO, Oulu, Finland, Turku, Finland, Brussels, Belgium, Gainesville, FL, Stanford, CA, Houston, TX
122-OR: Lower Plasma Levels of Truncated Apolipoprotein C-I Are Associated with Increased Risk of Diabetes—Multiethnic Study of Atherosclerosis
JURAJ KOSKA, YUEMING HU, DEAN BILLHEIMER, DOBRIN NEDELKOV, MATTHEW BUDOFF, ALAIN BERTONI, ROBYN MCCLELLAND, PETER REAVEN, Phoenix, AZ, Tucson, AZ, Sugar Land, TX, Los Angeles, CA, Winston-Salem, NC, Seattle, WA
210-OR: Discovering Stimulatory State-Specific Type 2 Diabetes GWAS Mechanisms with Single-Cell Multiomics on iPSC-Derived Fibro-adipogenic Progenitor Cell Villages
CHRISTA VENTRESCA, ARUSHI VARSHNEY, PETER ORCHARD, YAO-CHANG TSAN, ANDRE MONTEIRO DA ROCHA, MARKKU LAAKSO, SR., JAAKKO TUOMILEHTO, TIMO A. LAKKA, KAREN L. MOHLKE, MICHAEL BOEHNKE, LAURA SCOTT, HEIKKI A. KOISTINEN, FRANCIS S. COLLINS, TODD J. HERRON, STEPHANIE BIELAS, STEPHEN PARKER, Kuopio, Finland, Chapel Hill, NC, Helsinki, Finland, Bethesda, MD, Ann Arbor, MI
257-OR: The Effect of a Reduced-Energy Diet upon Maternal Weight and Pregnancy Outcomes in Women with Gestational Diabetes—The DiGest Trial
LAURA C. KUSINSKI, DANIELLE JONES, NOORIA ATTA, ELIZABETH TURNER, LINDA M. OUDE GRIEP, KIRSTEN L. RENNIE, EMANUELLA DE LUCIA ROLFE, STEPHEN SHARP, HELEN R. MURPHY, ROY TAYLOR, CLAIRE L. MEEK, Cambridge, United Kingdom, Norwich, United Kingdom, Newcastle upon Tyne, United Kingdom
261-OR: Single-Dose GLP-1-Based Pancreatic Gene Therapy Durably Maintains Body Composition and Glycemia after Semaglutide Withdrawal in a Murine Model of Obesity
ALICE L. FITZPATRICK, SUYA WANG, REBECCA REESE, NICOLE PICARD, EMILY COZZI, TIMOTHY J. KIEFFER, JAY CAPLAN, HARITH RAJAGOPALAN, Lexington, MA
337-OR: The LonP1 Protease Maintains Pancreatic ß-Cell Survival by Governing Mitochondrial Protein Folding
JIN LI, JIE ZHU, EMMA C. RECK, EMILY M. WALKER, SCOTT SOLEIMANPOUR, Ann Arbor, MI
Health Disparities Committee—Top 10 Recommended Abstracts
The “Health Disparities Committee’s Top 10 Recommended Abstracts” recognize health disparities related abstracts that have been accepted into the 84th Scientific Sessions of the American Diabetes Association®. These abstracts focus on health care disparities in diabetes outcomes, showcase research that explores the underlying factors in diabetes disparities, and demonstrate practical interventions that may contribute to eliminating those disparities.
652-P: Impact of a Six-Month Digital Health Coaching Program on Individuals with Type 2 Diabetes Mellitus Experiencing Food Insecurity in Rural Areas
JASMINE MOORE, SARAH RUTLAND, JANE MURPHY, MERCEDES TARASOVICH, Birmingham, AL.
544-P: Early Evidence from a Pragmatic Trial to Increase Uptake of Diabetes Self-Management Education and Support Services in Rural Health Care Systems in Kentucky
MARY E. LACY, JAMES KECK, JESSICA ELLIOTT, LAURA WRIGHT, VANCE H. DRAKEFORD, BRENT MCKUNE, AARON J. KRUSE-DIEHR, KEY DOUTHITT, Anchorage, AK, Lexington, KY, Jackson, KY.
1175-P: Mental Health and Glycemic Control Disparities among Latinx Adolescents with Type 1 Diabetes
ELIZABETH VARGAS, BAILEY TANNER, LAUREN B. SHOMAKER, HOLLY K. O'DONNELL, Aurora, CO, Fort Collins, CO.
1937-P: Coordinated Approach to Improve Quality of Care and Address Disparities in Patients with Cardiometabolic Disease—Analysis from the Cardiometabolic Center Alliance Registry
MIKHAIL N. KOSIBOROD, MELISSA L. MAGWIRE, EVAN L. O'KEEFE, DANIEL S. AISTROPE, EMILY ANDAYA, ANTHONY BASHALL, JAVED BUTLER, KATIE CUMMINGS, LISA DAVIS, ROBERT H. ECKEL, JONATHAN A. FIALKOW, LACY HARNESS, KEITH A. MILLER, IAN NEELAND, SHACHI PATEL, JORGE PLUTZKY, ROSALIE K. SAALFELD, ANDREA STAFOS, SANJAY RAJAGOPALAN, Kansas City, KS, Mission Hills, KS, Shelbyville, IN, Indianapolis, IN, Dallas, TX, Kansas City, MO, Miami, FL, Aurora, CO, Coral Gables, FL, Cleveland, OH, Boston, MA, Lincoln, NE, Baltimore, MD.
1930-LB: A Randomized Trial of Real-Time Continuous Glucose Monitoring (RT-CGM) with Culturally Tailored Education for Latino Patients with Type 2 Diabetes (DM)
NICOLE M. EHRHARDT, LORENA WRIGHT, LAURA MONTOUR, PETER BERBERIAN, EVELIN JONES, DARINKA D. GIL MENCHACA, ANA GABRIELA VASCONCELOS, BRYAN A. COMSTOCK, Burien, WA, Seattle, WA.
14-OR: Autonomous Artificial Intelligence Diabetic Eye Exams Mitigates Disparities in Screening Completion for Youth
DHRUVA PATEL, LEE A. BROMBERGER, NEHA PARIMI, ELIZABETH A. BROWN, ALVIN LIU, HAROLD LEHMANN, MICHAEL D. ABRÀMOFF, RISA M. WOLF, Baltimore, MD, Iowa City, IA.
208-OR: Impact of Carbohydrate-Restricted Nutrition Therapy and Continuous Remote Care among People with Type 2 Diabetes in Rural vs. Urban Areas
SHAMINIE J. ATHINARAYANAN, REBECCA N. ADAMS, CAROLINE G.P. ROBERTS, BRITTANIE M. VOLK, ALISON ZOLLER, AMY L. MCKENZIE, West Lafayette, IN, San Francisco, CA, Denver, CO.
1822-LB: Family Support for Diabetes Action (FAM-ACT) vs. Traditional Diabetes Management Education and Support—Randomized Comparative Effectiveness Trial
ANN-MARIE ROSLAND, GRETCHEN PIATT, EDITH C. KIEFFER, FELIX VALBUENA, GLORIA PALMISANO, DENISE J. DEVERTS, STEPHANIE PEREZ, JONATHAN YABES, CHRISTINA M. LALAMA, MICHELE HEISLER, Pittsburgh, PA, Ann Arbor, MI, Detroit, MI.
188-OR: Association of Social Determinants of Health with Efficacy of Metabolic Bariatric Surgery (MBS) vs. Medical Therapy (MT) for Type 2 Diabetes
MARY-ELIZABETH PATTI, BO HU, HANNA WANG, YAEL SARIG, DONALD C. SIMONSON, KATHY FOSTER, DANIELLE WOLFS, DAVID ARTERBURN, MATTHEW J. O'BRIEN, ASHLEY H. VERNON, JOHN M. JAKICIC, SANGEETA R. KASHYAP, ALI AMINIAN, PHILIP SCHAUER, DAVID E. CUMMINGS, WILLIAM F. GOURASH, ANITA COURCOULAS, JOHN P. KIRWAN, Cleveland, OH, Providence, RI, Seattle, WA, Chicago, IL, Boston, MA, Kansas City, KS, NY, NY, Baton Rouge, LA, Pittsburgh, PA.
1344-P: Socioeconomic Status Patterns in Remote Diabetic Retinopathy Screening Using Teleophthalmology
MARIA JESSICA CRUZ, TANVI CHOKSHI, LINDSEY NGUYEN, TREYSI G. VARGAS-RAMOS, ABRAHAM HANG, BLAKE M. SNYDER, GLENN YIU, Boston, MA, Sacramento, C.
ADA Interest Group Abstract Awards
Behavioral Medicine & Psychology
654- P: Insights on Inclusion—Tailoring a Health Insurance Toolkit to Diverse Emerging Adults with Type 1 Diabetes
CHANTEL S. SHANNON, ANUHYA K. KANCHIBHATLA, MARY JANE ROCHE, JORDEN RIEKE, CLAUDIA LEWIS, DIONNE A. WILLIAMS, ERIKA L. LUNDGRIN, BETUL HATIPOGLU, MICHELLE L. LITCHMAN, NANCY A. ALLEN, JULIA E. BLANCHETTE, Cleveland, OH, Boston, MA, Beachwood, OH, Salt Lake City, UT
Clinical Centers & Programs
746-P: GLP-1 RA and Risk of Malignancy in Patients with Type 2 Diabetes
FAIDAT A. ISHOLA, C. WILLIAM PIKE, SUN H. KIM, Stanford, CA, New York, NY
Diabetes & Cardiovascular Disease
245-OR: Proteomic Analysis of Mineralocorticoid Receptor Antagonism in Diabetic Atherosclerosis (MAGMA)—Results and Integrated Predictors of Response
ARMANDO VERGARA-MARTEL, JEAN-EUDES DAZARD, MIRELA DOBRE, KIM A. CONNELLY, JONNELLE EDWARDS-GLENN, GABRIEL TENSOL, CHERYL CAMERON, MARK CAMERON, SADEER G. AL-KINDI, ROBERT D. BROOK, MATTHEW R. WEIR, SANJAY RAJAGOPALAN, Cleveland, OH, Toronto, ON, Canada, Detroit, MI, Baltimore, MD
Diabetes In Primary Care
644-P: Racial Ethnic Disparities in Prescription of GLP1 Receptor Agonists for People at High Risk for Diabetes on Atypical Antipsychotics
JITHIN SAM VARGHESE, DAVID GOLDSMITH, RACHEL WAFORD, ROSETTE CHAKKALAKAL, MOHAMMED K. ALI, FRANCISCO J. PASQUEL, ROBERT O. COTES, Atlanta, GA
Diabetes In Youth
147-OR: Obesity Is Associated with Increased Clearance and Reduced Drug Exposure to Metformin in Youth with Type 2 Diabetes
SHYLAJA SRINIVASAN, KEVIN YEN, ALEXANDER FLOREN, RADA SAVIC, San Francisco, CA
Diabetes Self-Management Education & Support
579-P: ADA Diabetes Medical Management Plan Implementation—Barriers and Opportunities
CHRISTINE MARCH, JACQUELINE MCMANEMIN, MARGARET PELLIZZARI, JANET RODRIGUEZ, HENRY RODRIGUEZ, KAREN HARRIMAN, CRYSTAL WOODWARD, Pittsburgh, PA, Fairfax, VA, Lake Success, NY, Tampa, FL, Tamp, FL, Dunn Loring, VA, Arlington, VA
Diabetes Technology
37-OR: Effectiveness of Continuous Glucose Monitoring on Short-Term In-hospital Mortality among Frail Critically Ill Patients with COVID-19—An Exploratory, Prospective, Randomized, Open-Label, Parallel, Single-Center, Randomized Clinical Trial
WEI WANG, YUN SHEN, Shanghai, China, Baton Rouge, LA
Exercise Physiology
28-OR: Posttranslational Modifications in Skeletal Muscle Direct Divergent Metabolic Responses to Different Exercise Training Modes
MARK W. PATAKY, CARRIE J. HEPPELMANN, KYLE SEVITS, ANEESH K. ASOKAN, KATHERINE KLAUS, K. SREEKUMARAN NAIR, Rochester, MN
Eye Health
322-OR: Delaying Progression of Diabetic Retinopathy Worsen the Risk for Age-Related Macular Degeneration
WARD FICKWEILER, TANVI CHOKSHI, EMER O'DOHERTY, SURYA VISHVA TEJA JANGOLLA, NOLAN A. ZIEMNIAK, I-HSIEN WU, CRIS MARTIN JACOBA, SAMET GULKAS, ASSEL TALASPAYEVA, JERRY D. CAVALLERANO, LLOYD P. AIELLO, JENNIFER K. SUN, GEORGE L. KING, Chestnut Hill, MA, Boston, MA
Foot Care
172-OR: Lineage Tracing of Vasculogenic Fibroblasts In Vivo and Their Significance in the Rescue of Diabetic Ischemic Tissue
KANHAIYA SINGH, SUMIT S. VERMA, SASHWATI ROY, CHANDAN K. SEN, MANISHEKHAR KUMAR, Pittsburgh, PA
Health Care Delivery & Quality Improvement
1036-P: Cost-Effectiveness of Real-Time CGM vs. Self-Monitoring of Blood Glucose in People with Type 2 Diabetes on Intensive Insulin Therapy in Australia
HAMZA ALSHANNAQ, MOIN AHMED, GREGORY J. NORMAN, DAVID SIMMONS, San Diego, CA, Sydney, Australia, Campbelltown NSW, Australia
Immunology, Immunogenetics, & Transplantation
335-OR: Preliminary Results of Islet Survival in a Novel Biovascular Pancreas Implanted in Primates
MEHMET H. KURAL, KEVIN M. NASH, KALEB M. NAEGELI, HONG QIAN, JUAN WANG, ROBERT D. KIRKTON, LAURA E. NIKLASON, DURHAM, NC
Islet Biology, Development, & Function
103-OR: Signaling Mechanisms Underlying Islet Compensation in a Novel Mouse Model of ß-Cell Replication Deficiency
HANNAH R. FOSTER, SOPHIA SDAO, MELISSA ADAMS, BARAK BLUM, MATTHEW J. MERRINS, Madison, WI
Nutritional Science & Metabolism
17-OR: ADA Presidents' Select Abstract: Oral Bisphenol A Administration Decreased Peripheral Insulin Sensitivity in Healthy Adults
ADAM SEAL, STEVEN K. MALIN, ANDREW SCHAFFNER, MICHAEL R. HUBBARD, SARAH K. KEADLE, HANNAH BRUNNER-GAYDOS, ALIA A. ORTIZ, JANE E. NAKAMURA, CLARA MCMAHON, RACHEL BARNETT, ANITA H. KELLEHER, KELLY A. BENNION, SUZANNE PHELAN, TODD HAGOBIAN, San Luis Obispo, CA, New Brunswick, NJ, Gilbert, AZ, San, CA, Seattle, WA, San Francisco, CA
Pregnancy & Reproductive Health
1217-P: Insulin Sensitivity and Insulin Secretion Differentially Affect Birthweight and Postpartum Glucose
EMILY A. ROSENBERG, KAITLYN JAMES, DEEPTI PANT, SARAH HSU, ROBIN L. AZEVEDO, CHLOE MICHALOPOULOS, TANAYOTT THAWEETHAI, CAMILLE E. POWE, ARANTXA MEDINA BAEZ, Charleston, SC, Boston, MA, Bridgewater, MA
Public Health & Epidemiology
152-OR: Sex Differences in Metabolomics and Risk of Coronary Heart Disease in Type 2 Diabetes
YILIN YOSHIDA, DANTING LI, XIANG LI, VIVIAN FONSECA, FRANCK MAUVAIS-JARVIS, LU QI, New Orleans, LA
WIN ADA Abstract Awards
Basic Science: Islet Biology, Immunology, Physiology, or Obesity
112-OR: A Novel Function of Endothelial Insulin-Like Growth Factor-1 Receptor—Regulation of Gastrointestinal Microbiota as a Defensive Mechanism against Obesity-Induced Metabolic Dysfunction
NATALIE J. HAYWOOD, CHEUKYAU LUK, TIMOTHY S. FUTERS, MELANIE REAY, NATALLIA MAKAVA, ANNA SKROMNA, RICHARD CUBBON, MARK KEARNEY, Leeds, United Kingdom
Behavioral Medicine, Nutrition, Exercise, and Education
611-P: Effect of Continuous Glucose Monitoring (CGM) vs. Blood Glucose Monitoring (BGM) during a Nutrition Intervention on Time in Range (TIR)
HOLLY J. WILLIS, STEPHEN E. ASCHE, AMY L. MCKENZIE, REBECCA N. ADAMS, SHANNON KRIZKA, CAROLINE G.P. ROBERTS, BRITTANIE M. VOLK, SHAMINIE J. ATHINARAYANAN, ALISON R. ZOLLER, RICHARD M. BERGENSTAL, Minneapolis, MN, Bloomington, MN, Denver, CO, San Francisco, CA
Clinical Diabetes, Epidemiology, and Diabetes Complications
1895-LB: Fasting C-Peptide and Type 1 Diabetes Polygenic Score Predict Diabetic Ketoacidosis in People with Type 2 Diabetes in DECLARE-TIMI 58
YU MI KANG, GIORGIO E.M. MELLONI, AVIVIT CAHN, ITAMAR RAZ, FILIPE MOURA, DEEPAK L. BHATT, SILVIO E. INZUCCHI, LAWRENCE A. LEITER, DARREN K. MCGUIRE, JOHN WILDING, INGRID A. GAUSE-NILSSON, JAN OSCARSSON, NICHOLAS MARSTON, CHRISTIAN T. RUFF, MARC S. SABATINE, STEPHEN D. WIVIOTT, Jerusalem, Israel, Boston, MA, New Haven, CT, Toronto, ON, Canada, Dallas, TX, Liverpool, United Kingdom, Mölndal, Sweden
Sex as a Biological Variable
1437-P: Blood Pressure (BP) Trajectories and 32-Year Cardiovascular Disease (CVD) Incidence in Women and Men with Type 1 Diabetes (T1D)
RACHEL G. MILLER, TREVOR J. ORCHARD, TINA COSTACOU, Pittsburgh, PA