Banting Medal for Scientific Achievement - Professor Dame Frances Ashcroft | American Diabetes Association

2022 Banting Medal for Scientific Achievement
Professor Dame Frances Ashcroft

Banting Medal Lecture
"Metabolic regulation of insulin secretion in health and disease"

Dr. Frances Ashcroft is Professor of Physiology at the University of Oxford, a Fellow of Trinity College Oxford, and a Fellow of the Royal Society of London. She received her PhD from the Cambridge University and did post-doctoral studies with Drs Peter Stanfield (University of Leicester) and Susumu Hagiwara (UCLA). She established her own group at the University of Oxford in 1983, with a focus on insulin secretion regulation from the pancreatic beta-cell. She discovered that the KATP channel serves as the molecular link between changes in the blood glucose concentration and insulin secretion and (together with Professor Andrew Hattersley) that mutations in KATP channel genes cause neonatal diabetes. This has enabled patients with this disorder to switch from insulin injections to drug therapy. Her current focus is how chronic hyperglycaemia in diabetes impairs beta-cell metabolism and thereby insulin secretion. She has won several awards for her work including the Croonian Lecture (Royal Society), the L'Oréal/UNESCO For Women in Science Award (European Laureate), the Albert Renold Prize (European Association for the Study of Diabetes) and the Lewis Thomas Prize for Science Writing (Rockefeller University). In 2015 she was made Dame Commander of the Order of the British Empire. She has also written two popular science books: Life at the Extremes—the science of survival and The Spark of Life—electricity in the human body.

Please join us in celebrating Professor Dame Frances Ashcroft for her outstanding contributions to diabetes research.

Awards Ceremony Video