November - 10 - 2009
Data from 2,5760 consecutive patients attending the I. Pavel Diabetes Center in Bucharest were analyzed to determine the impact of diabetes on cancer-specific mortality. During a follow-up of 5.99 ± 1.69 years, there were 3.9% cancer-specific deaths, with standardized mortality ratios of 1.48, and 2.36 for patients with type 2 diabetes treated with oral antidiabetics and insulin, and of 1.71 for patients with type 1 diabetes. The results from adjusted Cox regression analyses showed a correlation between age of diabetes onset, male gender, type 1 diabetes (HR 1.8) and insulin-treated type 2 diabetes (HR1.6) with an increased risk of cancer mortality. These findings confirm the results from previous reports suggesting a higher risk of cancer mortality in patients with diabetes (Ioacara, S. et al. 20th World Diabetes Congress (October 18-22, Montreal) 2009, Abst 0938).