DNA samples and extensive phenotypic data are available from the American Diabetes Association's GENNID study (Genetics of NIDDM). GENNID has collected detailed family histories and a broad array of data on 170 large pedigrees, all of which contain at least one affected sib pair, with a total of 650 affected individuals and approximately 1,200 total subjects. Included are approximately 65 Caucasian, 60 Hispanic, 25 African American, and 20 Japanese American pedigrees.

In addition, GENNID also contains DNA and data on 1,000 additional affected sib pairs in each of three groups, African American, Caucasian, and Hispanic.

DNA and phenotypic data, including race, gender and age, are available for all members of the pedigrees. The data set includes multiple metabolic factors, including carbohydrate metabolism, lipid metabolism, and body size measures, as well as lifestyle variables obtained by questionnaire (e.g., employment, exercise, etc.). Full details of the study design can be found in the August 1996 issue of Diabetes Care.

Investigators interested in obtaining the DNA samples and/or data will need to submit a proposal to the Association that addresses the genetics of type 2 diabetes. Download the application to access GENNID materials (Updated May 2008).

The GENNID resource is ideally suited for genetic linkage and association studies as well as SNP discovery and typing. To receive a more detailed description of this valuable genetic resource, please contact:

American Diabetes Association
GENNID Resource
1701 North Beauregard Street
Alexandria, VA 22311
Phone: (703) 549-1500, ext. 2376
Email: fbreedy@diabetes.org 

Visit the GENNID online catalog for additional details.