A Graded Balanced Exercise Plan in a Weight Management Program Improves Walking Capacity and Risk Factor indicators in Obese Type 2 Diabetes Population
Abstract Number: 2513-PO
Authors: JACQUELINE I. SHAHAR, OSAMA HAMDY, ANN GOEBEL-FABBRI, GILL GRANT, ROBERTA CAPELSON, CATHY CARVER, JOAN BEATON, Boston, MA
Results: Obese people with type 2 diabetes are typically sedentary and at risk for developing severe complications and comorbidities. Exercise is a major element that has been shown to reduce weight and risk factor indicators. The purpose was to evaluate the efficacy of a 12-week exercise intervention, as a component of a comprehensive weight loss program, on diabetes and obesity risk factor indicators.
60 subjects (22 males) had a medical, nutritional, psychological, and exercise evaluation to participate in a weight loss program. Average age=57.9±9.9 years, duration=7.6±6.3 years, weight=240.2±43.7lbs, BMI=36.6±4.2kg/m2, HbA1c=7.3±1.3%, waist=46.9±5.3 inches, hip=50.2±4.4 inches, CRP=5.8±6.1mg/L, total cholesterol=156.9±29.6mg/dl, triglycerides=122.1±53.7mg/dl, LDL-C=94.5±28.9, and HDL-C=40.6±7.7.
Subjects completed a 6 minute Walk Test pre and post the 12-week exercise intervention. Average baseline values included: walking capacity=481.6±79.5 meters, 1 min recovery HR=90.0±14.6 bpm, and 3 min recovery HR=77.9±12.5 bpm. A clinical exercise physiologist conducted a weekly exercise session. Patients progressed from 20 minutes, 4 d/wk of exercise to 60 minutes 6 d/wk. The exercise intervention included aerobic (cross and interval training), resistance (circuit training), and flexibility (stretching) exercises. Patients also had dietary and behavioral modifications. A diabetologist and NP made medication changes as needed.
Walking capacity improved 46.9±31.1 meters (9.7±6.4%; p<0.0001). Average 1 min recovery HR reduced 8.9±18.3bpm (9.8±20.4%; p<0.01). Average 3 min recovery HR reduced 6.3±14.4bpm (8.1±18.5%; p<0.01). Weight decreased 23.2±9.4lbs (p<0.0001), BMI decreased 3.8±3.1kg/m2 (p <0.001), HbA1c decreased 0.9±1.0% (p<0.0001), waist decreased 3.6±2.4 inches (p <0.0001), hip decreased 2.7±1.9 inches (p<0.0001), CRP decreased 1.6±3.4mg/L (p<0.001), total cholesterol decreased 6.8±34.4mg/dl (p>0.05), triglycerides decreased 3.2±84.0mg/dl (p>0.05), LDL-C decreased 4.6±27.8mg/dl (p>0.05), and HDL-C decreased 0.5±6.1mg/dl (p>0.05).
The 12-week exercise intervention as a component of a comprehensive weight loss program improves walking capacity, weight loss, and several risk factor indicators in obese people with type 2 diabetes. Improved risk factor indicators through exercise help manage diabetes and decrease the likelihood of complications.