A Randomized Controlled Trial of Aerobic Exercise Versus Resistance Training in Older Patients with Type 2 Diabetes Mellitus
Abstract Number: 1089-P
Authors: SU-YEN GOH, CINDY L. W. NG, E. SHYONG TAI, CHEE ENG TAN, PETER H. K. ENG
Institutions: Singapore, Singapore
Results: Aim: To compare the effect of progressive resistance training versus aerobic exercise on glycemic control and metabolic profile in sedentary overweight older individuals with type 2 diabetes.
Design and methods: We performed an 8-week randomized controlled trial of aerobic exercise versus resistance training in 22 patients (mean age 58.2 ± 6.8 years) with suboptimal metabolic control (pre-enrollment mean HbA1c 8.5±1.2% and BMI 29.16±5.21).
Results: The group randomized to resistance (strength) training had a mean decrease in HbA1c of 0.56±0.50 % from a baseline of 8.7% (p=0.018) and also reported improvements in quality of life (SF36 questionnaire) in physical function and general health. There was also a drop in triglyceride profile (mean decrease of 0.48±0.70 mmol/L, p = 0.09) and body fat composition as measured by anthropometry and bio-electrical impedance. At the end of the eight-week regimen the patients remained weight-neutral. Conversely, the subjects in the aerobic exercise arm experienced an improvement in blood pressure control with a mean drop in systolic BP of 10.0±9.4 mmHg ( p=0.01) and 9.8±9.4 mmHg for diastolic BP (p = 0.004). The improvement in metabolic control was not as impressive as that attained in the resistance training group: the mean reductions in HbA1c and triglyceride levels were 0.28±0.94% and 0.11±0.33 mmol/L respectively and did not reach statistical significance.
Conclusions: Progressive resistance training does indeed have a beneficial effect on the metabolic profile of patients with type 2 diabetes and may have benefits over and above that of aerobic exercise. These findings translate into rational and individualized exercise prescriptions tailored for the elderly or those who are unable to participate in aerobic exercise programs.