Physical Activity and Glycemic Control in Young Well-Controlled Type 1 Diabetic Subjects
Abstract Number: 1008-P
Authors: MARIE-CHRISTINE DUB[Eacute], DENIS PRUD[apos]HOMME, SIMONE LEMIEUX, CAROLE LAVOIE, S. JOHN WEISNAGEL.
Institutions: Ste-Foy, QC, Canada; Ottawa, ON, Canada; Trois-Rivi[egrave]res, QC, Canada.
Results: The relationship between physical activity (PA) and glycemic control (HbA1c) in young type 1 diabetic adults have shown conflicting results. PA and energy intake (EI) were assessed by 3-d food and activity records in 39 young (age: 25.9 ± 7.6 yrs) well-controlled (HbA1c: 7.0 ± 0.8%) type 1 diabetic subjects. Daily insulin dosage was 0.8 ± 0.2 U/kg. Daily energy expenditure (EE) and frequency of participation in PA (kcal·kg-1·d-1) were measured and categorized according to their intensity on a 1-9 scale. Category 1 indicated very low EE such as sleeping and category 9 indicated very high EE such as running. There were positive relationships between EE6-9 and EI (r = 0.38) and the proportion of caloric intake derived from carbohydrate (r = 0.34, all P < 0.05). There was no relation between PA and either HbA1c, daily insulin dosage or BMI. Within subjects displaying moderate to high EE (EE6-9), those with higher EE (based on the median value) presented lower sum of skinfolds (83 ± 29 vs 109 ± 48 mm, P < 0.05) and a tendency for higher fat-free mass (65 ± 10 vs 57 ± 13 kg, P = 0.06). Interestingly, they also presented higher HbA1c (7.3 ± 0.9 vs 6.8 ± 0.6%) compared to those with lower EE. Similarly, subjects with lower HbA1c (based on the median value) seemed more sedentary (higher EE1-5) compared to those with higher HbA1c (P = 0.08). This suggests that well-controlled type 1 diabetic subjects who are highly physically active gain body composition advantages from their activities but may have trouble adequately balancing their HbA1c. This suggests that, in order to encourage these subjects to pursue their good lifestyle habits, better strategies to attain proper HbA1c will be required.